Advanced paternal age as a risk factor for neurodevelopmental disorders: a translational study
نویسندگان
چکیده
منابع مشابه
[Paternal age as a risk factor for congenital malformations].
BACKGROUND The role of advanced maternal age as a risk factor for congenital malformations in offspring is known. However, the influence of paternal age is not clear. AIM To evaluate the association between advanced paternal age and the risk for congenital malformations. PATIENTS AND METHODS Analysis of maternal and paternal age of cases (malformed newborns) and controls from ECLAMC Databas...
متن کاملAdvanced paternal age is a risk factor for schizophrenia in Iranians
BACKGROUND Since 1958 many, but not all studies have demonstrated that paternal age is a risk factor for schizophrenia. There may be many different explanations for differences between studies, including study design, sample size, collection criteria, heterogeneity and the confounding effects of environmental factors that can for example perturb epigenetic programming and lead to an increase in...
متن کاملMetabolic Syndrome as a Risk Factor for Osteoarthritis
Metabolic syndrome refers to a set of conditions that include high blood pressure, increased insulin level in the blood, the accumulation of the excess fat around the abdomen, and increased blood lipids. In metabolic syndrome, the vast majority of these conditions are simultaneously present, and the risk of developing heart disease, stroke, and diabetes rises. Besides, osteoarthritis or degen...
متن کاملPaternal age and psychiatric disorders: A review
We review the hypotheses concerning the association between the paternal age at childbearing and childhood psychiatric disorders (autism spectrum- and attention deficit/hyperactive disorder) and adult disorders (schizophrenia, bipolar-, obsessive-compulsive-, and major depressive disorder) based on epidemiological studies. Several hypotheses have been proposed to explain the paternal age effect...
متن کاملAdvanced paternal age and risk of fetal death: a cohort study.
A possible detrimental paternal age effect on offspring health due to mutations of paternal origin should be reflected in an association between paternal age and fetal loss. The authors used data from a prospective study of 23,821 pregnant women recruited consecutively to the Danish National Birth Cohort from 1997 to 1999 to assess the association between paternal age and fetal death. Fathers o...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Molecular Autism
سال: 2020
ISSN: 2040-2392
DOI: 10.1186/s13229-020-00345-2